Trinity researchers lead €3.2 million project targeted at degenerative retinal diseases

Posted on: 05 September 2022

The project (EYE-D) will target diseases that can result in severe loss of vision and are estimated to affect 224,000 people in Ireland, and 40 million people worldwide.

The funding for EYE-D was announced today by Simon Harris, Minister for Further and Higher Education, Research, Innovation and Science. Science Foundation Ireland will provide €1.6 million funding to EYE-D, matched by project partners.

The proposed partnership involves separate collaborations with three companies: Roche, Disarm/Eli Lilly, private ophthalmology clinic, Progressive Vision Research, and the charity Fighting Blindness Ireland.

Cumulatively, these groups will fund €1.6 million to advance various research programmes focused on identifying the underlying causes of degenerative eye diseases.

Professor Matthew Campbell said: 

“We are excited about the potential developments that will emerge from this grant.  Spearheading a project with a cumulative budget of €3.2 million will allow us to make a major impact on the international stage of vision research. In addition, our research endeavours put us in a perfect position to identify the cause of some of the most common forms of blindness.”

Co-PI, Professor Sarah Doyle, added:

“This funding will allow us to build on the major successes our group has had in understanding degenerative eye diseases. Added to this, we can now recruit the most talented group of scientists internationally and place Ireland at the forefront of vision research.”

Professors Matthew Campbell and Sarah Doyle in Trinity.

Professors Matthew Campbell and Sarah Doyle, pictured in Trinity.

Announcing the funding, Simon Harris, Minister for Further and Higher Education, Research, Innovation and Science, said:

“I am delighted to announce today this funding to the EYE-D research project. This research has the potential to have an invaluable impact in identifying treatments that help tackle degenerative eye diseases. This project will aim to put Ireland at the forefront of international research into degenerative eye disease. I wish the EYE-D team every success in the rollout of this project. My Department is delighted to be in a position to support this important work.”

Aideen Curtin, CEO, Progressive Vision Research, said: 

We are delighted to support and contribute to the fundamental research into degenerative retinal disease that this award will make possible. We hope that this research will increase our understanding of retinal disease and ultimately may lead to new treatments that will be sight-saving for many people.”

Anna Moran, interim CEOat Fighting Blindnesssaid:

“As Fighting Blindness strive to promote patient-focused vision research, we are proud to support Prof Campbell and Prof Doyle in the innovative EYE-D project. An important strategic aim for us is to build capacity in Ireland in the area of retinal disease. This project has great potential to make significant impact nationally and internationally to bring us a step closer to identifying possible treatments for these debilitating conditions.”

Professor Philip Nolan, Science Foundation Ireland, said:

“We are looking forward to working with the researchers and collaborators of EYE-D research project as they work to find solutions to vision loss caused by retinal diseases.The project highlights the impact that the Strategic Partnership Programme can deliver. I welcome the broad partnership involved in supporting this research which includes industry, charities and higher education institutes.”

TheEYE-D research project seeks to identify new therapeutic treatments for Age Related Macular Degeneration (AMD), glaucoma, and other inherited diseases that cause vision loss.

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Thomas Deane | Media Relations | deaneth@tcd.ie | +353 1 896 4685